Asst. Prof. Dr. EREN TOPLUTAŞ

Neurology

Medipol Mega University Hospital
EREN TOPLUTAŞ

Birthplace

YILDIRIM

Languages

ENGLISH

Medical Areas of Interest

  • Epilepsy and EEG 
  • movement disorders (Parkinson's disease) 
  • dementia and Alzheimer's disease, consciousness disorders
  • stroke (cerebrovascular diseases)
  •  headache 
  • neuromuscular diseases (EMG)
  • clinical neurophysiology

Highlights

Asst. Prof. Eren Toplutaş, MD was born in Bursa in 1991. He completed his undergraduate education at Bursa Uludağ University Faculty of Medicine and his Neurology specialization training at Istanbul Medipol University Faculty of Medicine, earning the title of Neurology (Brain and Nervous System Diseases) Specialist. He completed his PhD in Neuroscience at Istanbul Medipol University Institute of Health Sciences in 2025 and continues his academic career at the same university.

 Toplutaş, who serves as an Assistant Professor in the Department of Neurology at Istanbul Medipol University Faculty of Medicine, also works as an educator and researcher within the university's Health Sciences and Technologies Research Institute (SABİTA) and the Clinical Electrophysiology, Neuroimaging and Neuromodulation Laboratory within REMER, as well as the Brain and Cognition Research Center (BEYKOG). His main research areas are EEG microstate analysis, resting state brain networks, disturbances of consciousness, and non-invasive neuromodulation (rTMS, tDCS, tACS) methods.

 His work has been published in internationally indexed SCI/SCI-E journals such as Brain Topography and Frontiers in Neuroscience. He was among the co-authors of the international 'EEG-meta-microstates' consortium, led by Prof. Christoph M. Michel of the University of Geneva and involving leading centers worldwide, aimed at standardizing EEG microstate analysis. He has made unique contributions to his field with his studies on the effects of transcranial magnetic stimulation (rTMS) in Alzheimer's and Parkinson's diseases and on EEG-based objective biomarkers in consciousness disorders. He has presented numerous papers at national and international neurology, clinical neurophysiology, and biophysics congresses; and has participated in research projects supported by TÜBİTAK (The Scientific and Technological Research Council of Turkey).

 Eren currently accepts patients in the Neurology department at Medipol Mega University Hospital; provides diagnostic and treatment services for a wide range of diseases, primarily epilepsy and EEG, movement disorders (Parkinson's disease), dementia and Alzheimer's disease, consciousness disorders, and stroke. Toplutaş, MD aims to provide internationally recognized healthcare services to his patients by combining his academic expertise in clinical neurophysiology with current and evidence-based approaches.

Educations

2021

Istanbul Medipol University Faculty of Medicine, Neurology

2016

Uludağ University, Faculty of Medicine

Publications

Toplutaş, E., Aydın, F., & Hanoğlu, L. (2023). EEG Microstate Analysis in Patients with Disorders of Consciousness and Its Clinical Significance. Brain Topography, 1-11.

2) Hanoglu, L., Toplutas, E., Saricaoglu, M., Velioglu, H. A., Yildiz, S., & Yulug, B. (2022). Therapeutic role of repetitive transcranial magnetic stimulation in Alzheimer’s and Parkinson’s Disease: electroencephalography microstate correlates. Frontiers in Neuroscience, 16, 798558.

3) Koenig, T., Diezig, S., Kalburgi, S. N., Antonova, E., Artoni, F., Brechet, L., ... & Michel, C. M. (2023). EEG-meta-microstates: towards a more objective use of resting-state EEG microstate findings across studies. Brain topography, 1-14. 7.2. Articles published in other international peer-reviewed journals 7.3. Papers presented at international scientific meetings and published in proceedings a. Toplutaş, E., Budak, M., Aktürk, T., Yılmaz, N. H., & Hanoğlu, L. (2019). P01-S Quantitative EEG analysis in a patient with adult-onset subacute sclerosing panencephalitis. Clinical Neurophysiology, 130(7), e94. b. Aliyeva, T., Öztekin, M. F., & Toplutaş, E. (2020). Transient alien hand syndrome in ischemic lesions of the corpus callosum: A report of 3 cases. International Journal of Stroke. CV IN YÖK FORMAT İKPDB-F025- R2 2 / 3 27.07.2023 c. Aydin, F., Budak, M., Toplutas, E., Sarıcaoglu, M., Avunc, H., & Hanoglu, L. (2022). TH-222. Investigation of the effect of gamma transcranial alternating current stimulation with EEG in patients with disorder of consciousness. Clinical Neurophysiology, 141, S154-S155.

7.4. International books written or book chapters

7.5. Articles published in national peer-reviewed journals 1) Helvacı Yılmaz, N., Erdoğan, C., Kızılaslan, D., Arıcı Düz, Ö., Hanoğlu, L., & Toplutaş, E. (2019). Factors affecting prognosis in patients with Hypoxic Encephalopathy followed in intensive care. Journal of Ankara University Faculty of Medicine. 2) Topçuoğlu, M. A., Özdemir, A. Ö., Aykaç, Ö., Milanoğlu, A., Gökçe, M., Bavli, S., ... & Arsava, E. M. (2022). Gastrostomy in hospitalized patients with acute stroke: "NoroTek" Turkey point prevalence study subgroup analysis. Turkish Journal Of Neurology. 3) Topçuoğlu, M., Arsava, E., Özdemir, A., Şirin, H., Güler, A., Çetiner, M., ... & Yevgi, R. (2021). Hospital management of neurovascular disease in Turkey: Rationale, hypothesis, methods and descriptive characteristics (NOROTEK: Turkey Neurology One-Day Study). Turkish Journal of Cerebrovascular Diseases, 27(3).

7.6. Papers presented at national scientific meetings and published in proceedings a. Yaghouti, L. F., Enginar, H., Amil, B., Toplutaş, E., Hanoğlu, L., Ağargün, M. Y., ... & Alacacıoğlu, İ. (2021). Where is this music coming from? A case report of musical hallucinosis. Turkish Journal of Psychiatry. b. TOPLUTAŞ, E., HELVACI YILMAZ, N., & AYSAL, F., (2020). The Role of Differential Diagnosis in Amyotrophic Lateral Sclerosis.

1st National Clinical Neurophysiology EEG-EMG Virtual Congress, Turkey c. ALİYEVA, T., TOPLUTAŞ, E., HELVACI YILMAZ, N., & AYSAL, F., (2019). A Case of Decrement Positive Motor Neuron. 55th National Congress of Neurology-Antalya, Turkey d. TOPLUTAŞ, E., ARICI DÜZ, Ö., ASLAN, A. S., ALİYEVA, T., & AYSAL, F., (2019). Mononeuropathy Multiplex:

A Report of 2 Cases. 55th National Congress of Neurology-Antalya, Turkey e. HELVACI YILMAZ, N., ERDOĞAN, C., TOPLUTAŞ, E., KIZILASLAN, D., ARICI DÜZ, Ö., & HANOĞLU, L., (2018). Experience with Amantadine, Rivastigmine and Transcranial Direct Current Stimulation Applications in Patients with Hypoxic Encephalopathy. 54th National Congress of Neurology-Antalya, Turkey

7.7. Other publications 8. Projects 117S956, Investigation of the Clinical Effectiveness of Korean Acupuncture Treatment in Chronic Tension-Type Headache, 3001 - Starting R&D, Scholarship, Final report accepted, ARDEB, SBAG - Health Sciences Research Support Group, Project Participation/Departure Dates: 24.04.2018 - 15.03.2020, Project Start/End Dates: 15.03.2018 - 15.03.2020.

9. Administrative Duties

10. Memberships in Scientific and Professional Organizations 1.European Academy of Neurology - Full Membership 2.Turkish Neurological Society

3.Turkish Brain Research and Neuroscience Society (TÜBAS)

Memberships

  •  Turkish Neurological Society 
  •  Turkish Clinical Neurophysiology EEG-EMG Association
  •  EEG-meta-microstates International Research Consortium (co-author/participant)

Clinical Competencies

  • Clinical EEG and EMG evaluation; EEG microstate and quantitative EEG (qEEG) analysis; non-invasive neuromodulation (rTMS/tDCS/tACS) applications; neurophysiological data analysis and statistical modeling.

Scientific Activities

  • Research articles published in international journals indexed in SCI/SCI-E, primarily Brain Topography and Frontiers in Neuroscience
  •  Co-authorship in an international consensus study on the objective use of EEG microstate analysis (EEG-meta-microstates)
  •  Numerous oral and poster presentations at national and international neurology, clinical neurophysiology, and biophysics congresses; participation in TÜBİTAK (The Scientific and Technological Research Council of Turkey).-supported research projects

International Clinical Experience

Eren is involved in the international 'EEG-meta-microstates' consortium, led by Prof. Christoph M. Michel of the University of Geneva, which focuses on the standardization of EEG microstate analysis, and collaborates with centers such as the University of Miami, Peking University, and the 'G d'Annunzio' University of Chieti. He has also worked in the multicenter NöroTek (Turkish Neurology One-Day Study) stroke research network across Türkiye.

Additional Information

  •  EEG microstate analysis, resting state brain networks, and quantitative EEG (qEEG)
  •  Non-invasive neuromodulation (rTMS, tDCS, tACS), functional brain imaging, and objective biomarkers in impaired consciousness